GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| BLCA | cis | rs5758659 | 1 | rs134869 | chr22:42652074 | CCDC134 | chr22:42196678-42222303:+ | 0.26 | 4.26 | 2.58E-5 | Cognitive function |
| BLCA | cis | rs5758659 | 1 | rs134869 | chr22:42652074 | CYP2D6 | chr22:42522502-42526883:- | -0.38 | -8.08 | 8.39E-15 | Cognitive function |
| BLCA | cis | rs5758659 | 1 | rs134869 | chr22:42652074 | NAGA | chr22:42454339-42466846:- | 0.3 | 5.46 | 8.68E-8 | Cognitive function |
| BLCA | cis | rs5758659 | 1 | rs134873 | chr22:42657566 | C22orf32 | chr22:42475699-42480287:+ | 0.21 | 5.52 | 6.11E-8 | Cognitive function |
| BLCA | cis | rs5758659 | 1 | rs134873 | chr22:42657566 | CCDC134 | chr22:42196678-42222303:+ | 0.25 | 4.07 | 5.8E-5 | Cognitive function |
| BLCA | cis | rs5758659 | 1 | rs134873 | chr22:42657566 | CYP2D6 | chr22:42522502-42526883:- | -0.36 | -7.65 | 1.65E-13 | Cognitive function |
| BLCA | cis | rs5758659 | 1 | rs134873 | chr22:42657566 | NAGA | chr22:42454339-42466846:- | 0.3 | 5.31 | 1.88E-7 | Cognitive function |
| BLCA | cis | rs5758659 | 1 | rs134882 | chr22:42670965 | C22orf32 | chr22:42475699-42480287:+ | 0.2 | 5.25 | 2.52E-7 | Cognitive function |
| BLCA | cis | rs5758659 | 1 | rs134882 | chr22:42670965 | CCDC134 | chr22:42196678-42222303:+ | 0.24 | 4.01 | 7.3E-5 | Cognitive function |
| BLCA | cis | rs5758659 | 1 | rs134882 | chr22:42670965 | CYP2D6 | chr22:42522502-42526883:- | -0.36 | -7.78 | 6.79E-14 | Cognitive function |
| BLCA | cis | rs5758659 | 1 | rs134882 | chr22:42670965 | NAGA | chr22:42454339-42466846:- | 0.27 | 4.82 | 2.11E-6 | Cognitive function |
| BLCA | cis | rs5758659 | 1 | rs134900 | chr22:42683343 | C22orf32 | chr22:42475699-42480287:+ | 0.17 | 4.68 | 4.07E-6 | Cognitive function |
| BLCA | cis | rs5758659 | 1 | rs134900 | chr22:42683343 | CYP2D6 | chr22:42522502-42526883:- | -0.35 | -7.56 | 3.06E-13 | Cognitive function |
| BLCA | cis | rs5758659 | 1 | rs134900 | chr22:42683343 | NAGA | chr22:42454339-42466846:- | 0.26 | 4.59 | 5.95E-6 | Cognitive function |
| BLCA | cis | rs5758659 | 1 | rs134902 | chr22:42683997 | C22orf32 | chr22:42475699-42480287:+ | 0.17 | 4.57 | 6.47E-6 | Cognitive function |